Lung Spindle Cell Carcinoma

Preferred Label : Lung Spindle Cell Carcinoma;

NCIt definition : A morphologic variant of sarcomatoid carcinoma characterized by the presence of malignant spindle cells and focal lymphoplasmacytic infiltrates. Adenocarcinoma cells, malignant squamous cells, and giant cells are not present.;

Neoplastic status : Malignant;

Details

Origin ID

C45541;

UMLS CUI

C1708784;

Automatic exact mappings (from CISMeF team)
- Spindle cell carcinoma of lung [ICD-11 More detail]
- Spindle cell carcinoma of the lung [MedDRA LLT]
Currated CISMeF NLP mapping
- Primary spindle cell carcinoma of lung (disorder) [SNOMED CT concept]
- spindle cell carcinoma of lung [Disease (Nov.)]
Disease excludes abnormal cell
- Adenocarcinoma Cell [NCIt concept]
- Malignant Epithelial Giant Cell [NCIt concept]
- Malignant Epithelial Small Cell [NCIt concept]
- Malignant Squamous Cell [NCIt concept]
- Malignant Stromal Cell [NCIt concept]
- Neoplastic Smooth Muscle Cell [NCIt concept]
Disease may have findings
- Aggressive Clinical Course [NCIt concept]
- Cough [NCIt concept]
- Dyspnea [NCIt concept]
- Fever [NCIt concept]
- Hemoptysis [NCIt concept]
Excludes anatomical site(s)
- Neck [NCIt concept]
- Skin [NCIt concept]
Has associated anatomic sites
- Lung [NCIt concept]
- Respiratory System [NCIt concept]
- Thoracic Cavity [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- Spindle cell carcinoma of lung (disorder) [SNOMED CT concept]
- Spindle cell carcinoma of the lung [MedDRA LLT]
concept_is_in_subset
- CTRP Disease Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- NCIt Neoplasm Core Terminology [NCIt concept]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
- Premalignant Lesion [NCIt concept]
disease_has_abnormal_cell
- Malignant Cell [NCIt concept]
- Malignant Epithelial Cell [NCIt concept]
- Malignant Epithelial Spindle Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Epithelial Cell [NCIt concept]
disease_has_finding
- Anaplastic Lesion [NCIt concept]
- Carcinomatous Component Present [NCIt concept]
- Epithelial Component Present [NCIt concept]
- Lymphoplasmacytic Infiltrate [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
- Poorly Differentiated Lesion [NCIt concept]
disease_has_normal_cell_origin
- Epithelial Cell [NCIt concept]
disease_has_normal_tissue_origin
- Epithelial Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Lung [NCIt concept]
disease_mapped_to_gene
- TP53 Gene [NCIt concept]
disease_may_have_cytogenetic_abnormality
- Gain of Chromosome 12p [NCIt concept]
- Gain of Chromosome 13q [NCIt concept]
- Gain of Chromosome 17q [NCIt concept]
- Gain of Chromosome 5p [NCIt concept]
- Gain of Chromosome 9q [NCIt concept]
disease_may_have_molecular_abnormality
- TP53 Gene Inactivation [NCIt concept]
- TP53 Gene Mutation [NCIt concept]

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