NCIt synonyms : Thymic Extranodal Marginal Zone Lymphoma of Mucosa-Associated Lymphoid Tissue; Mediastinal Mucosa-Associated Lymphoid Tissue Lymphoma; Primary Thymic Extranodal Marginal Zone Lymphoma; MALT Lymphoma of the Mediastinum; Primary Thymus Extranodal Marginal Zone Lymphoma; Thymus Extranodal Marginal Zone Lymphoma of Mucosa-Associated Lymphoid Tissue; Thymic Mucosa-Associated Lymphoid Tissue Lymphoma;
NCIt definition : A low-grade extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue
that affects the thymus. It is characterized by the presence of centrocyte-like or
monocytoid lymphocytes that surround reactive lymphoid follicles. There is infiltration
of the thymic epithelium by lymphocytes and formation of lymphoepithelial lesions.
It is associated with the presence of autoimmune disease, most frequently Sjogren
syndrome. Patients are usually asymptomatic and the tumor is detected incidentally
as a mediastinal mass on chest x-ray. A minority of patients present with dyspnea,
hemoptysis, and chest pain. The prognosis is excellent.;