Preferred Label : Carcinoma ex Pleomorphic Adenoma;
NCIt synonyms : Carcinoma in Pleomorphic Adenoma; CXPA;
NCIt definition : A carcinoma arising in a pre-existing pleomorphic adenoma. It most often occurs in
the parotid gland and less often in the submandibular gland and minor salivary gland.
Patients usually present with a history of a long-standing mass which recently had
undergone rapid growth. The prognosis depends on the invasiveness of the malignant
component. Patients with non-invasive or minimally invasive tumors usually have a
good prognosis following surgical resection. Invasive tumors are usually aggressive
and are associated with recurrences and metastases.;