Clear Cell Intrahepatic Cholangiocarcinoma

Preferred Label : Clear Cell Intrahepatic Cholangiocarcinoma;

NCIt definition : A morphologic variant of intrahepatic cholangiocarcinoma composed of malignant glandular epithelium, an abundant fibrous stroma, and the presence of clear cells. Clinical symptoms include abdominal pain, weight loss and malaise.;

Neoplastic status : Malignant;

Details

Origin ID

C43848;

UMLS CUI

C1707406;

Disease excludes abnormal cell
- Malignant Squamous Cell [NCIt concept]
- Malignant Stromal Cell [NCIt concept]
- Neoplastic Smooth Muscle Cell [NCIt concept]
- Neoplastic Squamous Cell [NCIt concept]
Disease excludes normal cell origin
- Embryonic Cell [NCIt concept]
Disease may have findings
- Abdominal Pain [NCIt concept]
- Acinar Pattern [NCIt concept]
- Malaise [NCIt concept]
- Thorotrast Exposure [NCIt concept]
- Tubular Pattern [NCIt concept]
- Unfavorable Clinical Outcome [NCIt concept]
- Weight Loss [NCIt concept]
Excludes anatomical site(s)
- Extrahepatic Bile Duct [NCIt concept]
Has associated anatomic sites
- Bile Duct [NCIt concept]
- Biliary Tract [NCIt concept]
- Digestive System [NCIt concept]
- Hepatobiliary System [NCIt concept]
- Liver [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
- Favorable Clinical Outcome [NCIt concept]
- Intermediate Grade Neuroendocrine Lesion [NCIt concept]
- Low Grade Neuroendocrine Lesion [NCIt concept]
- Mixed Neoplastic Glandular and Squamous Cell Population [NCIt concept]
- Well Differentiated Neuroendocrine Lesion [NCIt concept]
disease_has_abnormal_cell
- Adenocarcinoma Cell [NCIt concept]
- Adenocarcinoma Clear Cell [NCIt concept]
- Malignant Cell [NCIt concept]
- Malignant Epithelial Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Epithelial Cell [NCIt concept]
- Neoplastic Glandular Cell [NCIt concept]
disease_has_finding
- Carcinomatous Component Present [NCIt concept]
- Epithelial Component Present [NCIt concept]
- Fibrotic Stroma Formation [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
disease_has_normal_cell_origin
- Epithelial Cell [NCIt concept]
disease_has_normal_tissue_origin
- Bile Duct Epithelium [NCIt concept]
- Epithelial Tissue [NCIt concept]
- Hepatobiliary Tissue [NCIt concept]
- Intrahepatic Bile Duct Epithelium [NCIt concept]
disease_has_primary_anatomic_site
- Bile Duct [NCIt concept]
- Biliary Tract [NCIt concept]
- Digestive System [NCIt concept]
- Hepatobiliary System [NCIt concept]
- Intrahepatic Bile Duct [NCIt concept]
- Liver [NCIt concept]
- Pancreatobiliary System [NCIt concept]
disease_may_have_molecular_abnormality
- KRAS Gene Amplification [NCIt concept]
- TP53 Gene Inactivation [NCIt concept]

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