Perianal Intraepithelial Neoplasia

Preferred Label : Perianal Intraepithelial Neoplasia;

NCIt synonyms : Anal Margin Squamous Dysplasia; Perianal Skin Bowen's Disease; PSIN; Anal Margin Bowen Disease; Bowen Disease; Anal Margin Intraepithelial Neoplasia; Perianal Squamous Dysplasia; Anal Margin Bowen's Disease; Perianal Skin Bowen Disease; Perianal Squamous Intraepithelial Neoplasia;

CISMeF acronym : PSIN;

NCIt definition : A precancerous neoplastic intraepithelial process involving the squamous epithelium of the perianal skin. Clinically, it usually presents as a white or red area in the perianal skin. Morphologically, it is characterized by full thickness dysplasia of the squamous epithelium and sometimes of the pilosebaceous epithelium. Human papillomavirus DNA sometimes may be identified in the dysplastic epithelium. It may recur after treatment, however only a small percentage of cases progress to squamous cell carcinoma.;

Neoplastic status : Undetermined;

Details

Origin ID

C43598;

UMLS CUI

C1332271;

Automatic exact mappings (from CISMeF team)
- BOWEN'S DISEASE [WHO-ART Included Term]
- Bowen disease [PASCAL descriptor]
- Bowen disease [ICD-O code]
- Bowen disease [ICD-11 Extension code]
- Bowen's disease [MedDRA Preferred Term]
- Bowen's disease [ICD-9 code]
- Bowen's disease (morphologic abnormality) [SNOMED CT concept]
- bowen's disease [MeSH Descriptor]
- bowen's disease [SNOMED Notion]
- bowen's disease [MeSH concept]
Disease excludes abnormal cell
- Neoplastic Glandular Cell [NCIt concept]
- Neoplastic Smooth Muscle Cell [NCIt concept]
Has associated anatomic sites
- Anus [NCIt concept]
- Digestive System [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
Validated automatic mappings to NTBT
- Bowen disease [Disease (Nov.)]
disease_excludes_finding
- Invasive Lesion [NCIt concept]
- Mixed Neoplastic Glandular and Squamous Cell Population [NCIt concept]
disease_has_abnormal_cell
- Dysplastic Epithelial Cell [NCIt concept]
- Dysplastic Squamous Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Epithelial Cell [NCIt concept]
- Neoplastic Squamous Cell [NCIt concept]
disease_has_finding
- Dysplasia [NCIt concept]
- Epithelial Component Present [NCIt concept]
disease_has_normal_cell_origin
- Epithelial Cell [NCIt concept]
- Squamous Cell [NCIt concept]
disease_has_normal_tissue_origin
- Epithelial Tissue [NCIt concept]
- Squamous Epithelium [NCIt concept]
disease_has_primary_anatomic_site
- Anal Margin [NCIt concept]
- Anus [NCIt concept]
- Digestive System [NCIt concept]

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