Small Intestinal Signet Ring Cell Adenocarcinoma

Preferred Label : Small Intestinal Signet Ring Cell Adenocarcinoma;

NCIt synonyms : Small Intestinal Signet-Ring Cell Carcinoma; Small Intestinal Signet Ring Cell Carcinoma;

NCIt definition : An invasive adenocarcinoma that arises from the small intestine. It is characterized by the presence of malignant glandular cells in which the nucleus is pressed to one side by the presence of intracytoplasmic mucus.;

Neoplastic status : Malignant;

Détails

Origin ID

C43543;

UMLS CUI

C1710110;

Disease excludes abnormal cell
- Malignant Squamous Cell [NCIt concept]
- Malignant Stromal Cell [NCIt concept]
- Neoplastic Smooth Muscle Cell [NCIt concept]
- Neoplastic Squamous Cell [NCIt concept]
Disease may have findings
- Abdominal Pain [NCIt concept]
- Fever [NCIt concept]
- Lower Gastrointestinal Hemorrhage [NCIt concept]
- Weight Loss [NCIt concept]
Has associated anatomic sites
- Digestive System [NCIt concept]
- Intestine [NCIt concept]
- Small Intestine [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
concept_is_in_subset
- NCIt Neoplasm Core Terminology [NCIt concept]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
- Intermediate Grade Neuroendocrine Lesion [NCIt concept]
- Intestinal Metaplasia [NCIt concept]
- Low Grade Neuroendocrine Lesion [NCIt concept]
- Mixed Neoplastic Glandular and Squamous Cell Population [NCIt concept]
- Mucoid Stroma Formation [NCIt concept]
- Well Differentiated Neuroendocrine Lesion [NCIt concept]
disease_has_abnormal_cell
- Adenocarcinoma Cell [NCIt concept]
- Malignant Cell [NCIt concept]
- Malignant Epithelial Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Epithelial Cell [NCIt concept]
- Neoplastic Glandular Cell [NCIt concept]
- Signet Ring Adenocarcinoma Cell [NCIt concept]
disease_has_finding
- Carcinomatous Component Present [NCIt concept]
- Epithelial Component Present [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
disease_has_normal_cell_origin
- Epithelial Cell [NCIt concept]
- Glandular Cell [NCIt concept]
- Small Intestinal Glandular Cell [NCIt concept]
disease_has_normal_tissue_origin
- Epithelial Tissue [NCIt concept]
- Glandular Epithelium [NCIt concept]
- Small Intestinal Mucosa [NCIt concept]
disease_has_primary_anatomic_site
- Digestive System [NCIt concept]
- Small Intestine [NCIt concept]
disease_may_have_associated_disease
- Crohn Disease [NCIt concept]
disease_may_have_cytogenetic_abnormality
- Loss of Chromosome 17p [NCIt concept]
- Loss of Chromosome 18q [NCIt concept]
- Loss of Chromosome 5q [NCIt concept]
disease_may_have_molecular_abnormality
- CTNNB1 Gene Mutation [NCIt concept]
- KRAS Gene Mutation [NCIt concept]
- Loss of CDH1 Protein Expression [NCIt concept]
- Microsatellite Instability [NCIt concept]
- SMAD4 Gene Inactivation [NCIt concept]
- TP53 Gene Inactivation [NCIt concept]

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