Diethylstilbestrol

Preferred Label : Diethylstilbestrol;

NCIt synonyms : Diethylstilbenediol; 3,4-Bis(p-hydroxyphenyl)-3-hexene; Diethylstilboestrol; (E)-4,4'-(1,2-diethyl-1,2-ethenediyl)bisphenol; Alpha,alpha'-diethylstilbenediol; Trans-bis-(hydroxy-4-phenyl)-3,4 hexene-3; 4,4'-Dihydroxy-alpha,beta-diethylstilbene; Diethylstilbestrolum;

NCIt related terms : Microest; Distilbene; Stilboestrol; Milestrol; Diastyl; DES; Oestromenin; Stilboestroform; Estrobene; Fonatol; 3-Hexene,3,4-bis(p-hydroxyphenyl)-; Stilboefral; Stilkap; Oestrogenine; Stilbestrol; Stilbetin; 3, 4-Bis(p-hydroxyphenyl)-3-hexene; Sexocretin; .alpha., .alpha.'-Diethylstilbenediol; Palestrol; Antigestil; Synestrin; Oestromensyl; 4,4'-Dihydroxy-.alpha., .beta.-diethylstilbene; Domestrol; Grafestrol; Cyren A; Vagestrol; Makarol; Estrosyn; Serral; Bufon; Sibol; diethylstilbestrol (DES);

NCIt definition : A synthetic, nonsteroidal form of estrogen. A well-known teratogen and carcinogen, diethylstilbestrol inhibits the hypothalamic-pituitary-gonadal axis, thereby blocking the testicular synthesis of testosterone, lowering plasma testosterone, and inducing a chemical castration.;

Alternative definition : NCI-GLOSS: A synthetic form of the hormone estrogen that was prescribed to pregnant women between about 1940 and 1971 because it was thought to prevent miscarriages. Diethylstilbestrol may increase the risk of uterine, ovarian, or breast cancer in women who took it. It also has been linked to an increased risk of clear cell carcinoma of the vagina or cervix in daughters exposed to diethylstilbestrol before birth.;

UNII : 731DCA35BT;

InChIKey : RGLYKWWBQGJZGM-ISLYRVAYSA-N;

CAS number : 56-53-1;

Drug name : Stilkap; Domestrol; Boestrol; Oestrogenine; Sexocretin; Palestrol; Estrobene; Antigestil; Microest; Serral; Grafestrol; Synthoestrin; Stilbestrol; Apstil; Stilboestrol; Estrosyn; Stilbetin; Estromenin; Oestromon; Distilbene; Cyren A; Oestromenin; Makarol; Oestromensyl; Synestrin; Milestrol; Fonatol; Sibol; Neo-Oestronol I; Stilboefral; Stilboestroform; Bufon; Diastyl; Acnestrol; Vagestrol;

Chemical formula : C18H20O2;

NSC code : 3070;

ChEBI ID : CHEBI:41922;

Codes from synonyms : CDR0000046021; NSC0003070; CDR0000044873; 159;

Details

Origin ID

C433;

UMLS CUI

C0012203;

Automatic exact mappings (from CISMeF team)
- Cerebellar ataxia, impaired intellectual development, and dysequilibrium syndrome 1 [OMIM Phenotype]
- Desmin [OMIM gene]
- Dysequilibrium syndrome (disorder) [SNOMED CT concept]
- Fetal diethylstilbestrol syndrome (disorder) [SNOMED CT concept]
- Stilbestrols [MeSH Descriptor]
- desmin [ORDO Gene]
- hoof and claw [MeSH Descriptor]
- snails [MeSH Descriptor]
- sulfur [MeSH Descriptor]
See also inter- (CISMeF)
- Product containing diethylstilbestrol (medicinal product) [SNOMED CT concept]
- diethylstilbestrol preparation [SNOMED Notion]
Semantic type(s)
- Hormone [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Diethylstilbestrol [ICD-11 Extension code]
- Diethylstilbestrol [LOINC component]
- Diethylstilbestrol (substance) [SNOMED CT concept]
- Product containing diethylstilbestrol (medicinal product) [SNOMED CT concept]
- diethylstilbestrol [ATC Code]
- diethylstilbestrol [ATC Code]
- diethylstilbestrol [ATC Code]
- diethylstilbestrol [Substance BNPC]
- diethylstilbestrol [MeSH concept]
- diethylstilbestrol [MeSH Descriptor]
- diethylstilbestrol preparation [SNOMED Notion]
Validated automatic mappings to BTNT
- diethylstilbestrol [ATC Code]
- diethylstilbestrol [ATC Code]
- diethylstilbestrol [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- HemOnc Agent Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- Operational Ontology for Radiation Oncology Prostate Cancer Terminology [NCIt concept]
is_component_of_chemotherapy_regimen
- Cyclophosphamide/Diethylstilbestrol/Fluorouracil [NCIt concept]
- Cyclophosphamide/Diethylstilbestrol/Fluorouracil/Methotrexate [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients