Malignancy in Giant Cell Tumor of Bone

Preferred Label : Malignancy in Giant Cell Tumor of Bone;

NCIt synonyms : Giant Cell Bone Sarcoma; Giant Cell Sarcoma of the Bone; Giant Cell Sarcoma of Bone; Malignancy in Giant Cell Tumor of the Bone; Malignant Giant Cell Tumor of Bone;

NCIt related terms : OSTEOCLASTOMA, MALIGNANT; Dedifferentiated Giant Cell Tumor; Giant cell tumor of bone, malignant;

NCIt definition : A malignant tumor that arises from the bone. It is characterized by the presence of an area of high grade sarcoma in an otherwise typical giant cell tumor (primary malignancy in giant cell tumor), or the presence of sarcoma in which the pre-existing giant cell tumor may or may not be apparent (secondary malignancy in giant cell tumor).;

Alternative definition : CDISC: A malignant neoplasm of bone comprised of osteoclast-like giant cells and mononuclear cells.;

Neoplastic status : Malignant;

ICD-O code : 9250/3;

Details

Origin ID

C4304;

UMLS CUI

C0334552;

Automatic exact mappings (from CISMeF team)
- Bone giant cell tumor malignant [MedDRA LLT]
- Bone giant cell tumour malignant [MedDRA Preferred Term]
- Giant cell tumor of bone, malignant [ICD-9 code]
- Giant cell tumour of bone, malignant [ICD-11 Extension code]
- bone giant cell sarcoma [DO Concept]
- giant cell tumor of bone [MeSH Descriptor]
Currated CISMeF NLP mapping
- Giant cell tumor of bone, malignant [ICD-O code]
- Giant cell tumor of bone, malignant (morphologic abnormality) [SNOMED CT concept]
- giant cell tumor of bone, malignant [SNOMED Notion]
DO Cross reference
- bone giant cell sarcoma [DO Concept]
Disease excludes abnormal cell
- Malignant Ovoid to Spindle-Shaped Fibrohistiocytic Cell [NCIt concept]
Disease excludes normal cell origin
- Bone Marrow Stem Cell [NCIt concept]
- Epithelial Cell [NCIt concept]
Excludes anatomical site(s)
- Lymphatic System [NCIt concept]
- Soft Tissue [NCIt concept]
Has associated anatomic sites
- Bone [NCIt concept]
- Connective and Soft Tissue [NCIt concept]
- Musculoskeletal System [NCIt concept]
See also inter- (CISMeF)
- Giant cell tumor of bone [ORDO Disease]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- Bone giant cell tumor malignant [MedDRA LLT]
- Bone giant cell tumour malignant [MedDRA Preferred Term]
- Giant cell tumor of bone, malignant [ICD-O code]
- Giant cell tumor of bone, malignant (morphologic abnormality) [SNOMED CT concept]
- bone giant cell sarcoma [DO Concept]
- giant cell tumor of bone, malignant [SNOMED Notion]
concept_is_in_subset
- CDISC SEND Terminology [NCIt concept]
- CDISC SEND Tumor Findings Results Terminology [NCIt concept]
- CTRP Disease Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- Cellosaurus Disease Terminology [NCIt concept]
- Cellosaurus Terminology [NCIt concept]
- Clinical Data Interchange Standards Consortium Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- Mapped ICDO3.1 Morphology PT Terminology [NCIt concept]
- Mapped ICDO3.1 Morphology Terminology [NCIt concept]
- Mapped ICDO3.1 Terminology [NCIt concept]
- Mapped ICDO3.2 Morphology PT Terminology [NCIt concept]
- Mapped ICDO3.2 Morphology Terminology [NCIt concept]
- Mapped ICDO3.2 Terminology [NCIt concept]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
- Indolent Clinical Course [NCIt concept]
- Intermediate Filaments Present [NCIt concept]
- Intracytoplasmic Eosinophilic Inclusion [NCIt concept]
disease_excludes_normal_tissue_origin
- Epithelial Tissue [NCIt concept]
disease_has_abnormal_cell
- Giant Cell [NCIt concept]
- Malignant Cell [NCIt concept]
- Malignant Connective and Soft Tissue Cell [NCIt concept]
- Malignant Mesenchymal Spindle Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Osteoclast-Like Giant Cell [NCIt concept]
disease_has_finding
- Lytic Bone Lesion [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
- Pain [NCIt concept]
- Swelling [NCIt concept]
disease_has_normal_cell_origin
- Cell [NCIt concept]
disease_has_normal_tissue_origin
- Connective Tissue [NCIt concept]
- Connective and Soft Tissue [NCIt concept]
- Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Bone [NCIt concept]

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