NCIt definition : A suspension composed of active and/or inert ingredient(s) encapsulated in liposomes
and intended for injection.;
Alternative definition : CDISC: A liquid parenteral pharmaceutical dosage form structured as a multilamellar
composition of concentric phospholipid spheres that encapsulate the drug (drug delivery
systems) separated by layers of water. Drug release is facilitated and controlled
by in vivo erosion of the liposomes. To further increase the in vivo circulation time,
liposomes in some preparations are covalently derivatized with PEG to produce PEGylated
or stealth liposomes. Covalent attachment of drugs to the outer surface of liposomes
can potentially serve as a delayed-release product. (NCI);