NCIt definition : A pellet covered with a thin layer of substance that is designed to release active
and/or inert ingredient(s) at a controlled, prolonged rate so as to reduce dosing
frequency.;
Alternative definition : CDISC: A solid dosage form in which the drug itself is in the form of granules to
which varying amounts of coating have been applied, and which releases a drug (or
drugs) in such a manner to allow a reduction in dosing frequency as compared to that
drug (or drugs) presented as a conventional dosage form. (NCI);