NCIt related terms : Granule, effervescent; GRAN EFFRV; Effervescent granules;
NCIt definition : A granule composed of active and/or inert ingredient(s), and a mixture of acids and
sodium bicarbonate, which release carbon dioxide when dissolved in water.;
Alternative definition : CDISC: A small particle or grain containing a medicinal agent in a dry mixture usually
composed of sodium bicarbonate, citric acid, and tartaric acid which, when in contact
with water, has the capability to release gas, resulting in effervescence. (NCI); EDQM-HC: Solid single-dose or multidose preparation consisting of uncoated granules
generally containing acidic substances and carbonates or hydrogen carbonates that
rapidly react in the presence of water to release carbon dioxide. Effervescent granules
are intended to be dissolved or dispersed in water before oral use.;