Diazoxide - CISMeF

Preferred Label : Diazoxide;

NCIt synonyms : 3-Methyl-7-chloro-1,2,4-benzothiadiazine 1,1-Dioxide;

NCIt definition : A benzothiadiazine derivate with antihypertensive and hyperglycemic activities. Diazoxide increases membrane permeability to potassium ions in vascular smooth muscle, thereby stabilizing the membrane action potential and preventing vascular smooth muscle contraction; this results in peripheral vasodilatation and decreases in peripheral vascular resistance. This agent also inhibits insulin release by interacting with ATP-sensitive potassium channels of pancreatic islet beta-cells.;

UNII : O5CB12L4FN;

InChIKey : GDLBFKVLRPITMI-UHFFFAOYSA-N;

CAS number : 364-98-7;

Drug name : Proglycem;

Molecule name : SRG-95213;

Chemical formula : C8H7ClN2O2S;

NSC code : 64198; 76130;

ChEBI ID : CHEBI:4495;

Codes from synonyms : 30277;

Details

Origin ID

C428;

UMLS CUI

C0012022;

Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Diazoxide [ICD-11 Extension code]
- Diazoxide [LOINC component]
- Diazoxide (substance) [SNOMED CT concept]
- Product containing diazoxide (medicinal product) [SNOMED CT concept]
- diazoxide [ATC Code]
- diazoxide [ATC Code]
- diazoxide [Substance BNPC]
- diazoxide [MeSH concept]
- diazoxide [SNOMED Notion]
- diazoxide [MeSH Descriptor]
Validated automatic mappings to BTNT
- diazoxide [ATC Code]
- diazoxide [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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