NCIt synonyms : Cellular Blue Nevus of the Skin; Cellular Blue Nevus of Skin; CBN;
NCIt definition : A blue nevus characterized by a multinodular cellular infiltrate with a dumb-bell
architecture occupying the reticular dermis. The cellular infiltrate often extends
into the subcutaneous tissue. The cellular infiltrate is composed of spindle-shaped
melanocytes with pale cytoplasm alternating with bundles of pigmented spindle-shaped
melanocytes. In occasional cases an increased mitotic activity, focal necrosis, and
nuclear pleomorphism may be seen. Such cases with atypical features may have an uncertain
malignant potential.;