NCIt definition : A pheochromocytoma that metastasizes to other anatomic sites. Common sites of metastasis
include lymph nodes, bones, liver, and lung. Morphologic features associated with
malignant pheochromocytomas include: atypical mitotic figures, capsular and vascular
invasion, tumor cell necrosis, and high mitotic activity.;
Alternative definition : CDISC: A malignant neoplasm of the adrenal gland medulla.;