Thyroid Gland Medullary Carcinoma with Amyloid Stroma

Preferred Label : Thyroid Gland Medullary Carcinoma with Amyloid Stroma;

NCIt synonyms : C Cell Adenocarcinoma with Amyloid Stroma; C Cell Carcinoma with Amyloid Stroma; Parafollicular Cell Carcinoma with Amyloid Stroma; Medullary Adenocarcinoma with Amyloid Stroma; Medullary Thyroid Gland Carcinoma with Amyloid Stroma; Medullary Carcinoma with Amyloid Stroma; Parafollicular Cell Adenocarcinoma with Amyloid Stroma;

NCIt definition : A medullary thyroid gland carcinoma characterized by the presence of amyloid stroma. The majority of medullary carcinomas of the thyroid gland are associated with amyloid deposits. The latter are highlighted with Congo red staining method.;

Neoplastic status : Malignant;

ICD-O code : 8345/3;

Details

Origin ID

C4193;

UMLS CUI

C0334379;

Currated CISMeF NLP mapping
- Medullary carcinoma with amyloid stroma [ICD-O code]
- Medullary carcinoma with amyloid stroma (morphologic abnormality) [SNOMED CT concept]
Disease excludes abnormal cell
- Large Osteoclastic Giant Cell [NCIt concept]
- Malignant Stromal Cell [NCIt concept]
- Neoplastic Smooth Muscle Cell [NCIt concept]
Disease may have findings
- Cold Nodule [NCIt concept]
- Metastatic Malignant Neoplasm in the Lymph Nodes [NCIt concept]
- Organoid Pattern [NCIt concept]
- Trabecular Pattern [NCIt concept]
Excludes anatomical site(s)
- Lung [NCIt concept]
- Pituitary Gland [NCIt concept]
Has associated anatomic sites
- Head and Neck [NCIt concept]
- Neck [NCIt concept]
- Thyroid Gland [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- Medullary carcinoma with amyloid stroma [ICD-O code]
- Medullary carcinoma with amyloid stroma (morphologic abnormality) [SNOMED CT concept]
concept_is_in_subset
- GDC Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- Mapped ICDO3.1 Morphology PT Terminology [NCIt concept]
- Mapped ICDO3.1 Morphology Terminology [NCIt concept]
- Mapped ICDO3.1 Terminology [NCIt concept]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
- Well Differentiated Neuroendocrine Lesion [NCIt concept]
disease_has_abnormal_cell
- Malignant Cell [NCIt concept]
- Malignant Endocrine Cell [NCIt concept]
- Malignant Epithelial Cell [NCIt concept]
- Malignant Neuroendocrine Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Endocrine Cell [NCIt concept]
- Neoplastic Epithelial Cell [NCIt concept]
- Neoplastic Neuroendocrine Cell [NCIt concept]
disease_has_finding
- Amyloid Deposition [NCIt concept]
- Calcitonin Positive Neoplastic Cells Present [NCIt concept]
- Carcinomatous Component Present [NCIt concept]
- Endocrine Differentiation [NCIt concept]
- Epithelial Component Present [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
- Neuroendocrine Differentiation [NCIt concept]
- Poorly Differentiated Neuroendocrine Lesion [NCIt concept]
- Serum Calcitonin Level Increased [NCIt concept]
- Well-Circumscribed Lesion [NCIt concept]
disease_has_molecular_abnormality
- Activating RET Gene Mutation [NCIt concept]
disease_has_normal_cell_origin
- C-Cell [NCIt concept]
- Epithelial Cell [NCIt concept]
disease_has_normal_tissue_origin
- Epithelial Tissue [NCIt concept]
- Thyroid Gland Epithelial Tissue [NCIt concept]
- Thyroid Gland Follicle [NCIt concept]
disease_has_primary_anatomic_site
- Head and Neck [NCIt concept]
- Neck [NCIt concept]
- Thyroid Gland [NCIt concept]
disease_mapped_to_gene
- RET Gene [NCIt concept]
disease_may_have_abnormal_cell
- Malignant Neuroendocrine Polygonal Cell [NCIt concept]
- Malignant Neuroendocrine Small Round Cell [NCIt concept]
- Malignant Neuroendocrine Spindle Cell [NCIt concept]
disease_may_have_associated_disease
- Paraneoplastic Syndrome [NCIt concept]

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