Ovarian Granulosa Cell

Preferred Label : Ovarian Granulosa Cell;

NCIt definition : A cuboidal cell derived from a spindle-shaped granulosa cell precursor. Initially, ovarian granulosa cells create a single layer surrounding an oocyte. The oocyte and its single layer of ovarian granulosa cells make up a primary follicle. Proliferation of the ovarian granulosa cells leads to multiple cell layers surrounding the oocyte and maturation into a secondary follicle. The granulosa cells extend cytoplasmic processes to form gestational gap-junction-like unions with the plasma membrane of the oocyte. The continued growth of the ovarian granulosa cells takes the oocyte to the Graafian follicle stage. Once ovulation occurs, the granulosa cells become part of the corpus luteum. A major function of an ovarian granulosa cell is hormone production and secretion.;

NCI Metathesaurus CUI : CL448674;

Details

Origin ID

C41607;

UMLS CUI

C0018207;

Anatomic structure is physical part of
- Endocrine Ovary [NCIt concept]
- Ovarian Follicle [NCIt concept]
- Ovarian Tissue [NCIt concept]
Currated CISMeF NLP mapping
- Granulosa cell of ovary [FMA entity]
- granulosa cells [MeSH concept]
- granulosa cells [MeSH Descriptor]
Semantic type(s)
- Cell [UMLS semantic type]
UMLS correspondences (same concept)
- Granulosa cell of ovary [FMA entity]
- granulosa cells [MeSH concept]
- granulosa cells [MeSH Descriptor]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients