Preferred Label : Danazol;
NCIt synonyms : DAN; 1-Ethynyl-2,3,3a,3b,4,5,10,10a,10b,11,12,12a-dodecahydro-10a,12a-dimethyl-1H-cyclopental[7,8]phenanthro[3,2-d]isoxazol-1-ol; (17Alpha)-pregna-2,4-dien-20-yno[2,3-d]-isoxazol-17-ol; 17Alpha-ethynyl-17beta-hydroxy-4-androsteno[2,3-d]isoxazole;
NCIt related terms : (17alpha)-Pregna-2,4-dien-20-yno[2,3-d]isoxazol-17-ol; Winobanin; Danocrine; Chronogyn; Danol; Win 17757;
NCIt definition : A synthetic androgen derived from ethinyl testosterone. Danazol indirectly reduces
estrogen production by decreasing pituitary secretion of follicle-stimulating hormone
and luteinizing hormone, and binds to sex hormone receptors in target tissues, thereby
exhibiting antiestrogenic, anabolic and weakly androgenic effects. (NCI04);
Alternative definition : NCI-GLOSS: A synthetic hormone that belongs to the family of drugs called androgens
and is used to treat endometriosis. It is being evaluated in the treatment of endometrial
cancer.;
UNII : N29QWW3BUO;
InChIKey : POZRVZJJTULAOH-LHZXLZLDSA-N;
CAS number : 17230-88-5;
Drug name : Chronogyn; Danol; Danocrine; Ladogal; Bonzol; Winobanin; Danoval; Cyclomen;
Molecule name : Win-17757;
Chemical formula : C22H27NO2;
NSC code : 270916;
ChEBI ID : CHEBI:4315;
Codes from synonyms : 05082; NSC0270916; CDR0000045188; 137;
Origin ID : C414;
UMLS CUI : C0010961;
See also inter- (CISMeF)
- Semantic type(s)
- UMLS correspondences (same concept)
- Validated automatic mappings to BTNT
- concept_is_in_subset
- is_component_of_chemotherapy_regimen
