Life Threatening or Disabling Adverse Event

Preferred Label : Life Threatening or Disabling Adverse Event;

NCIt synonyms : Life Threatening Adverse Event; Grade 4 Life Threatening or Disabling Adverse Event; Standard Toxicity Grade 4;

NCIt related terms : CTCAE Grade 4; 4; Grade 4; LIFE THREATENING; Common Terminology Criteria for Adverse Events Grade 4; Toxicity Value 4;

NCIt definition : Any adverse event that places the patient, in the view of the initial reporter, at immediate risk of death from the adverse event as it occurred, i.e., it does not include an adverse experience that, had it occurred in a more severe form, might have caused death.;

Alternative definition : CDISC: An adverse event, and/or its immediate sequelae, which is associated with an imminent risk of death or which is associated with physical or mental disabilities that affect or limit the ability of a person to perform activities of daily living (eating, ambulation, toileting, etc.) See NCI Common Terminology Criteria for Adverse Events.;

Details

Origin ID

C41337;

UMLS CUI

C3537125;

Automatic exact mappings (from CISMeF team)
- -4 (qualifier value) [SNOMED CT concept]
- 4 (qualifier value) [SNOMED CT concept]
- Arabic numeral 4 (qualifier value) [Inactive SNOMED CT concept]
- Grade 4 [ICD-11 Extension code]
- Grade 4 (qualifier value) [SNOMED CT concept]
- adenosylhomocysteinase like 1 [HGNC gene]
- grade 4 [Blood Transfusion thesaurus concept]
- inositol 1,4,5-triphosphate receptor associated 1 [HGNC gene]
- inositol polyphosphate phosphatase like 1 [HGNC gene]
- inositol polyphosphate-5-phosphatase A [HGNC gene]
- inositol polyphosphate-5-phosphatase B [HGNC gene]
- synaptojanin 1 [HGNC gene]
- synaptojanin 2 [HGNC gene]
Semantic type(s)
- Finding [UMLS semantic type]
concept_is_in_subset
- ALL Adverse Events Table [NCIt concept]
- ALL Authorized Value Terminology [NCIt concept]
- AML Adverse Events Table [NCIt concept]
- AML Authorized Value Terminology [NCIt concept]
- Adverse Event Outcome ICSR Terminology [NCIt concept]
- CDISC SDTM Terminology [NCIt concept]
- Clinical Data Interchange Standards Consortium Terminology [NCIt concept]
- EWS Adverse Events Table [NCIt concept]
- EWS Authorized Value Terminology [NCIt concept]
- FDA Individual Case Safety Report Terminology [NCIt concept]
- GCT Adverse Events Table [NCIt concept]
- GCT Authorized Value Terminology [NCIt concept]
- HL Adverse Events Table [NCIt concept]
- HL Authorized Value Terminology [NCIt concept]
- HL Late Effects Table [NCIt concept]
- OS Adverse Event Table [NCIt concept]
- OS Authorized Value Terminology [NCIt concept]
- Operational Ontology for Radiation Oncology Prostate Cancer Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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