Pancreatic Intraductal Papillary-Mucinous Neoplasm, High Grade

Preferred Label : Pancreatic Intraductal Papillary-Mucinous Neoplasm, High Grade;

NCIt synonyms : Pancreatic Intraductal Papillary Mucinous Neoplasm with High Grade Dysplasia; Pancreatic Non-Invasive Intraductal Papillary-Mucinous Carcinoma; Pancreatic Intraductal Papillary-Mucinous Neoplasm, High-Grade; Pancreatic Intraductal Papillary-Mucinous Neoplasm with High Grade Dysplasia;

NCIt definition : A non-invasive pancreatic intraductal papillary mucinous neoplasm characterized by the presence of neoplastic epithelial cells that exhibit loss of polarity, nuclear stratification, hyperchromasia, and pleomorphism. There is severe architectural atypia and frequent mitotic figures present.;

Neoplastic status : Uncertain Malignant Potential;

ICD-O code : 8453/2;

Details

Origin ID

C41251;

UMLS CUI

C1518873;

Automatic exact mappings (from CISMeF team)
- Intraductal papillary mucinous carcinoma of pancreas [ORDO Disease]
- Pancreatic Intraductal Neoplasms [MeSH Descriptor]
- pancreatic non-invasive intraductal papillary-mucinous carcinoma [DO Concept]
DO Cross reference
- pancreatic non-invasive intraductal papillary-mucinous carcinoma [DO Concept]
Disease excludes abnormal cell
- Neoplastic Smooth Muscle Cell [NCIt concept]
- Neoplastic Squamous Cell [NCIt concept]
Disease may have findings
- Abdominal Pain [NCIt concept]
- Cystic Change [NCIt concept]
- Diabetes Mellitus [NCIt concept]
- Jaundice [NCIt concept]
- Weight Loss [NCIt concept]
Has associated anatomic sites
- Digestive System [NCIt concept]
- Pancreas [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- pancreatic non-invasive intraductal papillary-mucinous carcinoma [DO Concept]
concept_is_in_subset
- GDC Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- Mapped ICDO3.1 Morphology PT Terminology [NCIt concept]
- Mapped ICDO3.1 Morphology Terminology [NCIt concept]
- Mapped ICDO3.1 Terminology [NCIt concept]
- Mapped ICDO3.2 Morphology PT Terminology [NCIt concept]
- Mapped ICDO3.2 Morphology Terminology [NCIt concept]
- Mapped ICDO3.2 Terminology [NCIt concept]
disease_excludes_finding
- Mild Dysplasia [NCIt concept]
- Mixed Neoplastic Glandular and Squamous Cell Population [NCIt concept]
- Moderate Dysplasia [NCIt concept]
- Stromal Invasion [NCIt concept]
- Tubular Pattern [NCIt concept]
disease_has_abnormal_cell
- Neoplastic Cell [NCIt concept]
- Neoplastic Epithelial Cell [NCIt concept]
- Neoplastic Glandular Cell [NCIt concept]
disease_has_finding
- Borderline Lesion [NCIt concept]
- Cystic Change [NCIt concept]
- Epithelial Component Present [NCIt concept]
- Intraductal Lesion [NCIt concept]
- Mucoid Stroma Formation [NCIt concept]
- Papillary Growth Pattern [NCIt concept]
- Severe Dysplasia [NCIt concept]
disease_has_normal_cell_origin
- Epithelial Cell [NCIt concept]
disease_has_normal_tissue_origin
- Epithelial Tissue [NCIt concept]
- Epithelium [NCIt concept]
disease_has_primary_anatomic_site
- Digestive System [NCIt concept]
- Exocrine Pancreas [NCIt concept]
- Pancreas [NCIt concept]
disease_mapped_to_gene
- KRAS Gene [NCIt concept]
disease_may_have_associated_disease
- Diabetes Mellitus [NCIt concept]
- Pancreatitis [NCIt concept]
disease_may_have_cytogenetic_abnormality
- Loss of Chromosome 17p [NCIt concept]
- Loss of Chromosome 18q [NCIt concept]
- Loss of Chromosome 9p [NCIt concept]
disease_may_have_molecular_abnormality
- BRAF Gene Mutation [NCIt concept]
- KRAS Gene Mutation [NCIt concept]
- TP53 Gene Inactivation [NCIt concept]

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