" /> Dactinomycin - CISMeF





Preferred Label : Dactinomycin;

NCIt synonyms : Actinomycin X 1; DACT; Actinomycin C1; Actinomycin A IV; Actinomycin-[thr-val-pro-sar-meval]; Meractinomycin; Actinomycin I1; 2-bis[Cyclo(N-methyl-L-valyl-sarcosyl-L-prolyl-D-valyl-L-threonyl)]-1,9 dimethyl-4,6 3H-phenoxazinone-3; Dactinomycine;

NCIt related terms : Actinomycin IV; Cosmegen; Lyovac cosmegen; ACTINOMYCIN D;

NCIt definition : A chromopeptide antineoplastic antibiotic isolated from the bacterium Streptomyces parvulus. Dactinomycin intercalates between adjacent guanine-cytosine base pairs, blocking the transcription of DNA by RNA polymerase; it also causes single-strand DNA breaks, possibly via a free-radical intermediate or an interaction with topoisomerase II. (NCI04);

Alternative definition : NCI-GLOSS: An anticancer drug that is a type of antitumor antibiotic.;

UNII : 1CC1JFE158;

InChIKey : RJURFGZVJUQBHK-IIXSONLDSA-N;

CAS number : 50-76-0;

Drug name : Lyovac Cosmegen; Cosmegen;

Chemical formula : C62H86N12O16;

NSC code : 3053;

ChEBI ID : CHEBI:27666;

Codes from synonyms : NSC0003053; CDR0000045237; 00417; 134;

Details


Keyword's position in hierarchy(ies) : arborescence

You can consult :


Nous contacter.
11/05/2025


[Home] [Top]

© Rouen University Hospital. Any partial or total use of this material must mention the source.