" /> Dactinomycin - CISMeF





Preferred Label : Dactinomycin;

NCIt synonyms : Actinomycin X 1; DACT; Actinomycin C1; Actinomycin A IV; Actinomycin-[thr-val-pro-sar-meval]; Meractinomycin; Actinomycin I1; 2-bis[Cyclo(N-methyl-L-valyl-sarcosyl-L-prolyl-D-valyl-L-threonyl)]-1,9 dimethyl-4,6 3H-phenoxazinone-3; Dactinomycine;

NCIt related terms : Actinomycin IV; Cosmegen; Lyovac cosmegen; ACTINOMYCIN D;

NCIt definition : A chromopeptide antineoplastic antibiotic isolated from the bacterium Streptomyces parvulus. Dactinomycin intercalates between adjacent guanine-cytosine base pairs, blocking the transcription of DNA by RNA polymerase; it also causes single-strand DNA breaks, possibly via a free-radical intermediate or an interaction with topoisomerase II. (NCI04);

Alternative definition : NCI-GLOSS: An anticancer drug that is a type of antitumor antibiotic.;

UNII : 1CC1JFE158;

InChIKey : RJURFGZVJUQBHK-IIXSONLDSA-N;

CAS number : 50-76-0; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 50-76-0 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Drug name : Lyovac Cosmegen; Cosmegen;

Chemical formula : C62H86N12O16;

NSC code : 3053;

ChEBI ID : CHEBI:27666;

Codes from synonyms : NSC0003053; CDR0000045237; 00417; 134;

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16/05/2024


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