NCIt synonyms : Pilomatrix Carcinoma of the Skin; Pilomatrix Carcinoma of Skin; Invasive Pilomatrixoma; Pilomatrix Skin Carcinoma; Pilomatrix Carcinoma;
NCIt related terms : Matrical carcinoma;
NCIt definition : A very rare, locally aggressive, malignant neoplasm of the hair follicle. The majority
of the cases arise de novo, however malignant transformation from a pre-existing pilomatricoma
has been reported. It usually presents as a solitary nodule in the head and neck,
upper extremities, or buttocks. Morphologically, it is characterized by the presence
of aggregates of basaloid cells infiltrating the dermis. Masses of ghost cells are
present in the cellular aggregates. Complete surgical excision is the treatment of
choice. If it is not completely removed, it usually recurs, but it rarely metastasizes
to distant anatomic sites.;