" /> Dacarbazine - CISMeF





Preferred Label : Dacarbazine;

NCIt synonyms : Dacarbazina; Dimethyl-triazeno-imidazole-carboximide; Dimethyl Triazeno Imidazol Carboxamide; Dimethyl Triazeno Imidazole Carboxamide; 5-(3-3-dimethyl-1-triazenyl)-1H-imidazole-4-carboxamide; 5(or 4)-(dimethyltriazeno)imidazole-4(or 5)-carboxamide; Imidazole Carboxamide Dimethyltriazeno; dimethyl-triazeno-imidazole carboxamide; DTIC; 1H-imidazole-4-carboxamide, 5-(3,3-dimethyl-1-triazenyl)-; Dimethyl (triazeno) imidazolecarboxamide; Biocarbazine; Dakarbazin; Dacarbazine - DTIC; DIC; Dacarbazina Almirall; DTIC-Dome;

NCIt related terms : 5-(Dimethyltriazeno)imidazole-4-carboxamide; 4-(Dimethyltriazeno)imidazole-5-carboxamide; Deticene; Imidazole carboxamide;

NCIt definition : A triazene derivative with antineoplastic activity. Dacarbazine alkylates and cross-links DNA during all phases of the cell cycle, resulting in disruption of DNA function, cell cycle arrest, and apoptosis. (NCI04);

Alternative definition : NCI-GLOSS: A drug that is used to treat Hodgkin lymphoma and malignant melanoma and is being studied in the treatment of other types of cancer. It attaches to DNA in cells and may kill cancer cells. It is a type of alkylating agent.;

UNII : 7GR28W0FJI;

InChIKey : FDKXTQMXEQVLRF-ZHACJKMWSA-N;

CAS number : 4342-03-4; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 4342-03-4 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Drug name : Asercit; Detimedac; Dacatic; Deticene; Fauldetic;

Molecule name : WR-139007;

Chemical formula : C6H10N6O;

NSC code : 45388;

ChEBI ID : CHEBI:4305;

Codes from synonyms : CDR0000045260; CDR0000635680; NSC0045388; 132;

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Keyword's position in hierarchy(ies) : arborescence

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15/05/2024


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