Prostatic Intraepithelial Neoplasia

Preferred Label : Prostatic Intraepithelial Neoplasia;

NCIt synonyms : PIN - Prostatic Intraepithelial Neoplasia;

NCIt related terms : Prostate intraepithelial neoplasia (PIN); PIN; Prostate intraepithelial neopl.;

NCIt definition : A neoplastic proliferation of the epithelial cells that line the acini and the ducts of the prostate gland. The neoplastic epithelial cells are confined within the acini and the ducts and they do not invade the surrounding prostatic stroma. Morphologically, it is classified as low or high grade.;

Alternative definition : NCI-GLOSS: Noncancerous growth of cells lining the internal and external surfaces of the prostate gland. Having high-grade PIN may increase the risk of developing prostate cancer.;

Neoplastic status : Undetermined;

Codes from synonyms : CDR0000403141; 10036912; CDR0000044345;

Details

Origin ID

C4064;

UMLS CUI

C0282612;

Currated CISMeF NLP mapping
- Prostatic intraepithelial neoplasia [MedDRA LLT]
- Prostatic intraepithelial neoplasia (disorder) [SNOMED CT concept]
- intraepithelial prostate neoplasm [Disease (Nov.)]
- prostatic intraepithelial neoplasia [MeSH Descriptor]
- prostatic intraepithelial neoplasia [MeSH concept]
Disease excludes abnormal cell
- Dysplastic Squamous Cell [NCIt concept]
- Neoplastic Smooth Muscle Cell [NCIt concept]
- Neoplastic Squamous Cell [NCIt concept]
Has associated anatomic sites
- Genitourinary System [NCIt concept]
- Male Reproductive System [NCIt concept]
- Prostate Gland [NCIt concept]
- Reproductive System [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- Prostatic intraepithelial neoplasia [MedDRA LLT]
- Prostatic intraepithelial neoplasia (disorder) [SNOMED CT concept]
- intraepithelial prostate neoplasm [Disease (Nov.)]
- prostatic intraepithelial neoplasia [MeSH concept]
- prostatic intraepithelial neoplasia [MeSH Descriptor]
concept_is_in_subset
- NCI CTEP SDC Prostatic Intraepithelial Neoplasia (PIN) Sub-Category Terminology [NCIt concept]
- NCI CTEP Simplified Disease Classification Terminology [NCIt concept]
disease_excludes_finding
- Invasive Lesion [NCIt concept]
- Mixed Neoplastic Glandular and Squamous Cell Population [NCIt concept]
disease_has_abnormal_cell
- Dysplastic Glandular Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Epithelial Cell [NCIt concept]
- Neoplastic Glandular Cell [NCIt concept]
disease_has_finding
- Dysplasia [NCIt concept]
- Epithelial Component Present [NCIt concept]
disease_has_normal_cell_origin
- Epithelial Cell [NCIt concept]
- Glandular Cell [NCIt concept]
disease_has_normal_tissue_origin
- Epithelial Tissue [NCIt concept]
- Glandular Epithelium [NCIt concept]
disease_has_primary_anatomic_site
- Prostate Gland [NCIt concept]
disease_may_have_cytogenetic_abnormality
- Gain of Chromosome 10 [NCIt concept]
- Gain of Chromosome 12 [NCIt concept]
- Gain of Chromosome 7 [NCIt concept]
- Gain of Chromosome 8q [NCIt concept]
- Gain of Chromosome Y [NCIt concept]
- Loss of Chromosome 10q [NCIt concept]
- Loss of Chromosome 16q [NCIt concept]
- Loss of Chromosome 18q [NCIt concept]
- Loss of Chromosome 8p [NCIt concept]
disease_may_have_molecular_abnormality
- TP53 Gene Inactivation [NCIt concept]

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