High Grade Cervical Squamous Intraepithelial Neoplasia

Preferred Label : High Grade Cervical Squamous Intraepithelial Neoplasia;

NCIt synonyms : High-Grade CIN; High-Grade Cervical SIL; High-Grade Cervical Squamous Intraepithelial Lesion; HSIL of Cervix; High Grade Cervical Squamous Intraepithelial Lesion; High-Grade Cervical Squamous Intraepithelial Neoplasia;

NCIt definition : A precancerous neoplastic process that affects the cervical squamous epithelium. It is usually associated with human papillomavirus infection. It is classified as cervical squamous intraepithelial neoplasia 2 when there is nuclear atypia in both the upper and lower epithelial layers, mitotic figures are confined to the basal two-thirds of the epithelium, and maturation is present in the upper half of the epithelium. It is classified as cervical squamous intraepithelial neoplasia 3 when there is nuclear atypia and mitotic figures throughout the entire thickness of the epithelium, and maturation is absent or confined to the upper third of the epithelium.;

Neoplastic status : Undetermined;

Details

Origin ID

C40197;

UMLS CUI

C1512433;

Currated CISMeF NLP mapping
- Cervical high grade squamous intraepithelial lesion [MedDRA LLT]
Disease excludes abnormal cell
- Neoplastic Glandular Cell [NCIt concept]
- Neoplastic Smooth Muscle Cell [NCIt concept]
Has associated anatomic sites
- Cervix Uteri [NCIt concept]
- Female Reproductive System [NCIt concept]
- Genitourinary System [NCIt concept]
- Reproductive System [NCIt concept]
- Uterus [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- Cervical high grade squamous intraepithelial lesion [MedDRA LLT]
disease_excludes_finding
- Invasive Lesion [NCIt concept]
- Mixed Neoplastic Glandular and Squamous Cell Population [NCIt concept]
disease_has_abnormal_cell
- Dysplastic Squamous Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Epithelial Cell [NCIt concept]
- Neoplastic Squamous Cell [NCIt concept]
disease_has_finding
- Dysplasia [NCIt concept]
- Epithelial Component Present [NCIt concept]
disease_has_grade
- High Grade [NCIt concept]
disease_has_normal_cell_origin
- Epithelial Cell [NCIt concept]
- Squamous Cell [NCIt concept]
disease_has_normal_tissue_origin
- Cervix Epithelium [NCIt concept]
- Epithelial Tissue [NCIt concept]
- Squamous Epithelium [NCIt concept]
disease_has_primary_anatomic_site
- Cervix Uteri [NCIt concept]
- Female Reproductive System [NCIt concept]
- Uterus [NCIt concept]
disease_may_have_associated_disease
- Human Papillomavirus Infection [NCIt concept]

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