High Grade Prostatic Intraepithelial Neoplasia, Inverted Variant

Preferred Label : High Grade Prostatic Intraepithelial Neoplasia, Inverted Variant;

NCIt synonyms : High-Grade Prostatic Intraepithelial Neoplasia Inverted Variant; High-Grade Prostatic Intraepithelial Neoplasia, Inverted Variant;

NCIt definition : High grade prostatic intraepithelial neoplasia characterized by the presence of secretory cells with their nuclei polarized towards the lumen of the glands.;

Neoplastic status : Undetermined;

Details

Origin ID

C39890;

UMLS CUI

C1512436;

Disease excludes abnormal cell
- Dysplastic Squamous Cell [NCIt concept]
- Neoplastic Smooth Muscle Cell [NCIt concept]
- Neoplastic Squamous Cell [NCIt concept]
Has associated anatomic sites
- Genitourinary System [NCIt concept]
- Male Reproductive System [NCIt concept]
- Prostate Gland [NCIt concept]
- Reproductive System [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
disease_excludes_finding
- Invasive Lesion [NCIt concept]
- Mixed Neoplastic Glandular and Squamous Cell Population [NCIt concept]
disease_has_abnormal_cell
- Dysplastic Glandular Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Epithelial Cell [NCIt concept]
- Neoplastic Glandular Cell [NCIt concept]
disease_has_finding
- Dysplasia [NCIt concept]
- Epithelial Component Present [NCIt concept]
- Polarization of Nuclei Towards the Glandular Lumen [NCIt concept]
disease_has_grade
- High Grade [NCIt concept]
disease_has_normal_cell_origin
- Epithelial Cell [NCIt concept]
- Glandular Cell [NCIt concept]
disease_has_normal_tissue_origin
- Epithelial Tissue [NCIt concept]
- Glandular Epithelium [NCIt concept]
disease_has_primary_anatomic_site
- Prostate Gland [NCIt concept]
disease_may_have_cytogenetic_abnormality
- Gain of Chromosome 10 [NCIt concept]
- Gain of Chromosome 12 [NCIt concept]
- Gain of Chromosome 7 [NCIt concept]
- Gain of Chromosome 8q [NCIt concept]
- Gain of Chromosome Y [NCIt concept]
- Loss of Chromosome 10q [NCIt concept]
- Loss of Chromosome 16q [NCIt concept]
- Loss of Chromosome 18q [NCIt concept]
- Loss of Chromosome 8p [NCIt concept]
disease_may_have_molecular_abnormality
- MYC Gene Amplification [NCIt concept]
- PTEN Gene Inactivation [NCIt concept]
- TMPRSS2-ERG Fusion Protein Expression [NCIt concept]
- TP53 Gene Inactivation [NCIt concept]

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