Chronic Lymphoproliferative Disorder of NK-Cells

Preferred Label : Chronic Lymphoproliferative Disorder of NK-Cells;

NCIt synonyms : CLPD-NK; NK-Cell Large Granular Lymphocyte Lymphocytosis; Chronic NK-LGL Lymphoproliferative Disorder; Indolent NK-Cell Lymphoproliferative Disorder; Chronic NK-Cell Lymphocytosis; Chronic NK-Large Granular Lymphocyte Lymphoproliferative Disorder; Indolent Large Granular NK-Cell Lymphoproliferative Disorder; NK-Type Lymphoproliferative Disorder of Granular Lymphocytes; NK-Large Granular Lymphocytic Leukemia; NK Large Granular Lymphocytic Leukemia;

NCIt related terms : Chronic lymphoproliferative disorder of NK cells; NK-LGLL; NK-LGL leukemia; natural killer-cell large granular lymphocyte leukemia;

NCIt definition : An Epstein-Barr virus negative disorder with a chronic clinical course affecting predominantly adults and characterized by the proliferation of large granular lymphocytes with natural killer cell immunophenotype. The T-cell receptor genes are not rearranged.;

Alternative definition : NCI-GLOSS: A type of leukemia in which large natural killer (NK) cells (a type of white blood cell) that contain granules (small particles) are found in the blood. It is a chronic disease that may last for a long time and get worse.;

Neoplastic status : Benign;

Concept status : Provisional_Concept;

ICD-O code : 9831/3;

Codes from synonyms : CDR0000659612; CDR0000644322; CDR0000644323;

Details

Origin ID

C39591;

UMLS CUI

C1512709;

Automatic exact mappings (from CISMeF team)
- Chronic lymphoproliferative disorder of NK cells [ICD-11 Extension code]
- Chronic lymphoproliferative disorder of natural killer cells [ORDO Disease]
- Chronic lymphoproliferative disorder of natural killer cells (disorder) [SNOMED CT concept]
- Chronic lymphoproliferative disorders of NK-cells [ICD-11 Subcategory]
- chronic NK-cell lymphocytosis [DO Concept]
- leukemia, large granular lymphocytic [MeSH Descriptor]
- leukemia, natural killer cell large granular lymphocytic [MeSH concept]
DO Cross reference
- chronic NK-cell lymphocytosis [DO Concept]
Disease excludes abnormal cell
- Neoplastic B-Lymphocyte [NCIt concept]
Disease excludes normal cell origin
- Myeloid Cell [NCIt concept]
- Precursor Natural Killer Cell [NCIt concept]
- Precursor T-Lymphoblast [NCIt concept]
Has associated anatomic sites
- Hematopoietic and Lymphatic System [NCIt concept]
- Lymphatic System [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- Chronic lymphoproliferative disorder of natural killer cells (disorder) [SNOMED CT concept]
- chronic NK-cell lymphocytosis [DO Concept]
concept_is_in_subset
- CTRP Disease Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- Cellosaurus Disease Terminology [NCIt concept]
- Cellosaurus Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
disease_excludes_molecular_abnormality
- Clonal Gene Rearrangement [NCIt concept]
disease_has_abnormal_cell
- Abnormal Large Granular Lymphocyte [NCIt concept]
- Abnormal Lymphocyte [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Hematopoietic and Lymphoid Cell [NCIt concept]
- Neoplastic Lymphocyte [NCIt concept]
- Neoplastic T-Lymphocyte and Neoplastic Natural Killer Cell [NCIt concept]
disease_has_finding
- Indolent Clinical Course [NCIt concept]
- Non-Malignant Cellular Infiltrate [NCIt concept]
disease_has_normal_cell_origin
- Hematopoietic and Lymphoid Cell [NCIt concept]
- Lymphocyte [NCIt concept]
- Natural Killer Cell [NCIt concept]
- Peripheral (Post-Thymic) T-Lymphocyte and Natural Killer Cell [NCIt concept]
- T-Lymphocyte and Natural Killer Cell [NCIt concept]
disease_has_normal_tissue_origin
- Hematopoietic and Lymphoid Tissue [NCIt concept]
- Lymphoid Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Hematopoietic and Lymphatic System [NCIt concept]
- Lymphatic System [NCIt concept]
disease_may_have_associated_disease
- Nephrotic Syndrome [NCIt concept]
- Vasculitis [NCIt concept]

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