T-Cell Large Granular Lymphocyte Leukemia Expressing the T-Cell Receptor Gamma-Delta

Preferred Label : T-Cell Large Granular Lymphocyte Leukemia Expressing the T-Cell Receptor Gamma-Delta;

NCIt synonyms : T-Cell Large Granular Lymphocyte Leukemia Expressing the TCR Gamma-Delta;

NCIt definition : An uncommon variant of T-cell large granular lymphocyte leukemia expressing the gamma-delta T-cell receptor. Approximately 60% of these cases are CD8-positive and the remainder are CD4/CD8-negative.;

Neoplastic status : Malignant;

Details

Origin ID

C39586;

UMLS CUI

C1515129;

Disease excludes abnormal cell
- Leukemic Plasma Cell [NCIt concept]
- Neoplastic B-Lymphocyte [NCIt concept]
Disease excludes normal cell origin
- Myeloid Cell [NCIt concept]
- Precursor Natural Killer Cell [NCIt concept]
- Precursor T-Lymphoblast [NCIt concept]
Disease may have findings
- Granulocytopenia [NCIt concept]
- Hypergammaglobulinemia [NCIt concept]
- Indolent Clinical Course [NCIt concept]
Has associated anatomic sites
- Hematopoietic and Lymphatic System [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
concept_is_in_subset
- NCIt Neoplasm Core Terminology [NCIt concept]
disease_excludes_finding
- Acute Clinical Course [NCIt concept]
- Benign Cellular Infiltrate [NCIt concept]
- Solid Growth Pattern [NCIt concept]
disease_has_abnormal_cell
- Abnormal Lymphocyte [NCIt concept]
- Leukemic Cell [NCIt concept]
- Leukemic Lymphocyte [NCIt concept]
- Malignant Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Hematopoietic and Lymphoid Cell [NCIt concept]
- Neoplastic Lymphocyte [NCIt concept]
- Neoplastic T-Cell Large Granular Lymphocyte [NCIt concept]
- Neoplastic T-Lymphocyte and Neoplastic Natural Killer Cell [NCIt concept]
disease_has_finding
- Malignant Cellular Infiltrate [NCIt concept]
- Splenomegaly [NCIt concept]
disease_has_normal_cell_origin
- Gamma/Delta T-Lymphocyte [NCIt concept]
- Hematopoietic and Lymphoid Cell [NCIt concept]
- Lymphocyte [NCIt concept]
- Mature T-Lymphocyte [NCIt concept]
- Peripheral (Post-Thymic) T-Lymphocyte and Natural Killer Cell [NCIt concept]
- T-Lymphocyte and Natural Killer Cell [NCIt concept]
disease_has_normal_tissue_origin
- Hematopoietic and Lymphoid Tissue [NCIt concept]
- Lymphoid Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Bone Marrow [NCIt concept]
- Hematopoietic and Lymphatic System [NCIt concept]
- Lymphatic System [NCIt concept]
disease_may_have_associated_disease
- Anemia [NCIt concept]
- Rheumatoid Arthritis [NCIt concept]
disease_may_have_cytogenetic_abnormality
- t(14;14)(q11;q32) [NCIt concept]
disease_may_have_molecular_abnormality
- FAS Apoptosis Pathway Deregulation [NCIt concept]

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