" /> Esophageal Leukoplakia - CISMeF





Preferred Label : Esophageal Leukoplakia;

NCIt synonyms : Leukoplakia of the Esophagus; Esophagus Leukoplakia; Leukoplakia of Esophagus; Esophageal Epidermoid Metaplasia;

NCIt definition : A rare condition that usually affects the middle-to-distal esophagus in middle-aged and elderly people. There is usually a history of tobacco smoking or alcohol intake. Dysphagia is the presenting symptom. Morphologically, the lesions are well-demarcated and are characterized by epithelial hyperplasia, thickened basal layer, prominent granular cell layer, and hyperorthokeratosis. In a minority of patients this condition is associated with adjacent high-grade squamous dysplasia and/or squamous cell carcinoma.;

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08/05/2025


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