Therapeutic Corticotropin-Releasing Factor

Preferred Label : Therapeutic Corticotropin-Releasing Factor;

NCIt synonyms : Corticoliberin; Recombinant Human Corticotropin Releasing Factor; Corticorelin; CFR; Therapeutic Corticotropin Releasing Factor;

NCIt definition : Any synthetic therapeutic agent which is chemically identical to or similar to the endogenous human corticotropin-releasing factor (hCRF). Synthesized in the hypothalamus, hCRF stimulates the anterior pituitary gland to secrete adrenocorticotropic hormone (ACTH). In cerebral edema, hCRF acts by impeding the flow of fluid from blood vessels into brain tissue, thereby decreasing edema and stabilizing intracranial pressure. This agent possesses anti-edema properties independent of adrenal gland function. (NCI05);

UNII : 305OE8862Y;

CAS number : 86784-80-7;

Chemical formula : C208H344N60O63S2;

NCI Metathesaurus CUI : CL324578;

Details

Origin ID

C394;

UMLS CUI

C0772289;

Automatic exact mappings (from CISMeF team)
- Catalytic Fraction [LOINC Property]
- Catalytic fraction (property) (qualifier value) [SNOMED CT concept]
- Corticorelin [ICD-11 Extension code]
- Corticotropin releasing hormone [LOINC component]
- Corticotropin-Releasing hormone [MeSH concept]
- Corticotropin-releasing factor [FMA entity]
- corticorelin [ATC Code]
- corticotropin releasing factor [SNOMED Notion]
- corticotropin releasing hormone [ORDO Gene]
- corticotropin releasing hormone [HGNC gene]
- corticotropin-releasing hormone [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Hormone [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- corticorelin [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients