NCIt definition : Substances administered during imaging procedures that allows delineation of internal
structures. Contrast agents appear opaque due to the difference in absorption of X-rays
or other electromagnetic waves and surrounding tissue.;
Alternative definition : NCI-GLOSS: A dye or other substance that helps show abnormal areas inside the body.
It is given by injection into a vein, by enema, or by mouth. Contrast material may
be used with x-rays, CT scans, MRI, or other imaging tests.;
NCIt note : Positive contrast agents have greater absorption and structures appear light. Negative
contrast agents have a lesser degree of absorption and structures appear dark.;