Preferred Label : Elongation Factor 1B1;
Obsolete resource : true;
NCIt synonyms : EF-1-Beta1; EEF1B1; Eukaryotic Translation Elongation Factor 1 Beta 1; Elongation Factor-1-Beta1; Elongation Factor-1B1;
NCIt definition : Encoded by human EEF1B1 Gene (EF1Beta/EF1Delta Family), 224-aa 24.6-kDa Elongation
Factor 1B1 is a subunit of heterotrimeric Elongation Factor 1 (containing alpha/beta/gamma
or alpha/delta/gamma subunits). Composed of an alpha subunit nucleotide binding domain
and a beta/gamma subunit nucleotide exchange complex, Elongation Factor 1 is responsible
for delivery of aminoacyl tRNAs to the ribosome. The homologous guanine nucleotide
exchange factor EF-1-beta and EF-1-delta subunits stimulate GDP/GTP exchange bound
to EF-1-alpha; phosphorylation affects the GDP/GTP exchange rate. (NCI);
NCIt note : Wed Jun 19 19:54:11 GMT 2013 - EEF1B1 is the same as EEF1B2P1 which is a pseudogene.
Elongation factor 1-beta is encoded by the EEF1B2 gene, see C38962.;
Concept status : Retired_Concept;
Origin ID : C38960;
UMLS CUI : C1516805;
OMIM relation
- Semantic type(s)
