High Affinity Interleukin-2 Receptor

Preferred Label : High Affinity Interleukin-2 Receptor;

Obsolete resource : true;

NCIt synonyms : Interleukin-2 Receptor;

NCIt definition : Expressed on T- and B-cells, human heterodimeric High Affinity Interleukin-2 Receptor consists of IL2RA and IL2RB subunits, associated with a common IL2RG chain, and mediates IL2 mitogenic signaling. Homodimeric IL2RA chains constitute a low-affinity non-signaling receptor, while homodimeric IL2RB chains produce a medium-affinity signaling receptor. IL2RG comprises a signaling component of many interleukin receptors (IL2, IL4, IL7, IL9, and IL15). (NCI);

NCIt note : See 'Interleukin-2 Receptor(C104679)';

Concept status : Retired_Concept;

NCI Metathesaurus CUI : CL449415;

Details

Origin ID

C38952;

UMLS CUI

C0034819;

Currated CISMeF NLP mapping
- Interleukin 2 receptor [LOINC component]
- Interleukin-2 receptor (substance) [SNOMED CT concept]
- interleukin-2 receptor site [SNOMED Notion]
- receptors, Interleukin-2 [MeSH concept]
- receptors, interleukin-2 [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- Interleukin 2 receptor [LOINC component]
- Interleukin-2 receptor (substance) [SNOMED CT concept]
- interleukin-2 receptor site [SNOMED Notion]
- receptors, Interleukin-2 [MeSH concept]
- receptors, interleukin-2 [MeSH Descriptor]

Keyword's position in hierarchy(ies) :

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