Glycosaminoglycan Biosynthesis Pathway - Keratan Sulfate

Preferred Label : Glycosaminoglycan Biosynthesis Pathway - Keratan Sulfate;

NCIt synonyms : Keratan Sulfate Biosynthesis Pathway;

NCIt related terms : Glycosaminoglycan Biosynthesis - Keratan Sulfate; Keratan Sulfate Biosynthesis;

Alternative definition : KEGG: Keratan sulfate (KS) is a glycosaminoglycan with the basic disaccharide unit of N-acetyllactosamine, Gal(b1-4)GlcNAc(b1-3), with sulfate esters at C-6 of GlcNAc and Gal residues. There are two types of KS distinguished by the protein linkage: type I for N-linked via the N-glycan core structure and type II for O-linked via the O-glycan core 2 structure.;

NCI Metathesaurus CUI : CL322995;

KEGG ID : hsa00533;

Details

Origin ID

C38830;

UMLS CUI

C1156904;

Automatic exact mappings (from CISMeF team)
- keratan sulfate biosynthetic process [GO term]
Semantic type(s)
- Molecular Function [UMLS semantic type]
UMLS correspondences (same concept)
- keratan sulfate biosynthetic process [GO term]
has_gene_product_element
- Beta-1,4-Galactosyltransferase 1 [NCIt concept]
- CMP-N-Acetylneuraminate-Beta-Galactosamide-Alpha-2,3-Sialyltransferase 2 [NCIt concept]
pathway_has_gene_element
- B4GALT1 wt Allele [NCIt concept]
- ST3GAL2 wt Allele [NCIt concept]

Keyword's position in hierarchy(ies) :

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