Thyroid Gland Anaplastic Carcinoma

Preferred Label : Thyroid Gland Anaplastic Carcinoma;

NCIt synonyms : Anaplastic Thyroid Carcinoma; Thyroid Gland Carcinosarcoma; Undifferentiated Carcinoma of Thyroid; Anaplastic Thyroid Cancer; Anaplastic Carcinoma of the Thyroid; Pleomorphic Thyroid Gland Carcinoma; Sarcomatoid Thyroid Gland Carcinoma; Anaplastic Carcinoma of Thyroid Gland; Undifferentiated Carcinoma of Thyroid Gland; Undifferentiated Carcinoma of the Thyroid; Undifferentiated Carcinoma of the Thyroid Gland; Anaplastic Carcinoma of the Thyroid Gland; Anaplastic Thyroid Gland Carcinoma; Dedifferentiated Thyroid Gland Carcinoma; Undifferentiated Thyroid Carcinoma; Metaplastic Thyroid Gland Carcinoma; Undifferentiated (Anaplastic) Thyroid Gland Carcinoma; Anaplastic Carcinoma of Thyroid; Undifferentiated Thyroid Gland Carcinoma; Thyroid Gland Pleomorphic Carcinoma; Thyroid Gland Undifferentiated (Anaplastic) Carcinoma; Thyroid Gland Metaplastic Carcinoma; Thyroid Gland Sarcomatoid Carcinoma; Thyroid Gland Giant Cell Carcinoma; ATC; Thyroid Gland Spindle Cell Carcinoma; Anaplastic Follicular Cell Derived Thyroid Carcinoma; Anaplastic Follicular Cell Derived Thyroid Gland Carcinoma;

NCIt related terms : Undifferentiated (Anaplastic) Thyroid Gland Cancer; Undifferentiated Thyroid Tumor;

NCIt definition : A primary carcinoma of the thyroid gland composed of undifferentiated cells. The malignant cells demonstrate evidence of epithelial differentiation, either by immunohistochemistry or electron microscopic studies. Microscopically, in the majority of cases there is a mixture of spindle, epithelioid, and giant cells. The vast majority of the patients present with a rapidly enlarging neck mass. The clinical course is usually aggressive.;

Alternative definition : NCI-GLOSS: A rare, aggressive type of thyroid cancer in which the malignant (cancer) cells look very different from normal thyroid cells.; NICHD: An aggressive carcinoma of the thyroid gland composed of undifferentiated cells.;

Neoplastic status : Malignant;

Codes from synonyms : CDR0000044541; 10002240;

Details

Origin ID

C3878;

UMLS CUI

C0238461;

Automatic exact mappings (from CISMeF team)
- Ataxia-telangiectasia [OMIM Phenotype]
- angioplasty, balloon, coronary [MeSH Descriptor]
- antidepressive agents, tricyclic [MeSH Descriptor]
Currated CISMeF NLP mapping
- Anaplastic thyroid cancer [MedDRA Preferred Term]
- Anaplastic thyroid carcinoma [PASCAL descriptor]
- Anaplastic thyroid carcinoma [HPO term]
- Anaplastic thyroid carcinoma [ORDO Disease]
- Anaplastic thyroid carcinoma (disorder) [SNOMED CT concept]
- Thyroid Carcinoma, Anaplastic [MeSH Descriptor]
- Thyroid Carcinoma, Anaplastic [MeSH concept]
- Undifferentiated carcinoma of thyroid gland [ICD-11 Subcategory]
- anaplastic thyroid cancer [Disease (Nov.)]
- anaplastic thyroid carcinoma [Radlex concept]
- thyroid gland anaplastic carcinoma [DO Concept]
DO Cross reference
- thyroid gland anaplastic carcinoma [DO Concept]
Disease excludes abnormal cell
- Malignant Stromal Cell [NCIt concept]
- Neoplastic Smooth Muscle Cell [NCIt concept]
Disease may have findings
- Aggressive Clinical Course [NCIt concept]
- Coagulative Necrosis [NCIt concept]
- Dysphagia [NCIt concept]
- Dyspnea [NCIt concept]
- Hoarseness [NCIt concept]
- Vocal Cord Paralysis [NCIt concept]
Has associated anatomic sites
- Head and Neck [NCIt concept]
- Neck [NCIt concept]
- Thyroid Gland [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- Anaplastic thyroid cancer [MedDRA Preferred Term]
- Anaplastic thyroid carcinoma [ORDO Disease]
- Anaplastic thyroid carcinoma [HPO term]
- Anaplastic thyroid carcinoma [PASCAL descriptor]
- Anaplastic thyroid carcinoma (disorder) [SNOMED CT concept]
- Thyroid Carcinoma, Anaplastic [MeSH concept]
- Thyroid Carcinoma, Anaplastic [MeSH Descriptor]
- Undifferentiated carcinoma of thyroid gland [ICD-11 Subcategory]
- anaplastic thyroid cancer [Disease (Nov.)]
- anaplastic thyroid carcinoma [Radlex concept]
- thyroid gland anaplastic carcinoma [DO Concept]
Validated automatic mappings to NTBT
- anaplastic thyroid cancer [Disease (Nov.)]
concept_is_in_subset
- CTRP Disease Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- Cellosaurus Disease Terminology [NCIt concept]
- Cellosaurus Terminology [NCIt concept]
- NCI CTEP SDC Thyroid Cancer Sub-Category Terminology [NCIt concept]
- NCI CTEP Simplified Disease Classification Terminology [NCIt concept]
- NCIt Neoplasm Core Terminology [NCIt concept]
- NICHD Terminology [NCIt concept]
- Pediatric Endocrinology Terminology [NCIt concept]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
- Glandular Differentiation [NCIt concept]
- Squamous Differentiation [NCIt concept]
disease_has_abnormal_cell
- Anaplastic Carcinoma Cell [NCIt concept]
- Malignant Cell [NCIt concept]
- Malignant Epithelial Cell [NCIt concept]
- Malignant Epithelial Large Cell [NCIt concept]
- Malignant Epithelial Spindle Cell [NCIt concept]
- Malignant Epithelioid Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Epithelial Cell [NCIt concept]
- Undifferentiated Carcinoma Cell [NCIt concept]
disease_has_finding
- Carcinomatous Component Present [NCIt concept]
- Epithelial Component Present [NCIt concept]
- High Mitotic Activity [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
- Rapidly Enlarging Mass [NCIt concept]
disease_has_normal_cell_origin
- Epithelial Cell [NCIt concept]
disease_has_normal_tissue_origin
- Epithelial Tissue [NCIt concept]
- Thyroid Gland Epithelial Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Head and Neck [NCIt concept]
- Neck [NCIt concept]
- Thyroid Gland [NCIt concept]
disease_may_have_molecular_abnormality
- BRAF NP_004324.2:p.V600E [NCIt concept]
- HRAS Gene Mutation [NCIt concept]
- KRAS Gene Mutation [NCIt concept]
- NRAS Gene Mutation [NCIt concept]
- PTEN Gene Inactivation [NCIt concept]
- TERT Promoter Mutation [NCIt concept]
- TP53 Gene Mutation [NCIt concept]

Keyword's position in hierarchy(ies) :

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