Thyroid Gland Sclerosing Mucoepidermoid Carcinoma with Eosinophilia

Preferred Label : Thyroid Gland Sclerosing Mucoepidermoid Carcinoma with Eosinophilia;

NCIt synonyms : Sclerosing Mucoepidermoid Thyroid Carcinoma with Eosinophilia; Sclerosing Mucoepidermoid Thyroid Gland Carcinoma with Eosinophilia; SMECE;

NCIt definition : A rare type of mucoepidermoid carcinoma of the thyroid gland, usually associated with chronic lymphocytic thyroiditis. It exhibits a unique morphologic appearance consisting of a squamoid, nested growth pattern, dense fibrosis, and mucinous differentiation. The histogenesis of this unusual carcinoma has been debated, and it is unclear if it arises from remnants of the ultimobranchial body or from the follicular epithelial cells.;

Neoplastic status : Malignant;

Details

Origin ID

C38763;

UMLS CUI

C1519204;

Disease excludes abnormal cell
- Malignant Stromal Cell [NCIt concept]
- Neoplastic Smooth Muscle Cell [NCIt concept]
Disease may have findings
- Cold Nodule [NCIt concept]
- Globular Hyaline Body [NCIt concept]
- Indolent Clinical Course [NCIt concept]
- Well-Circumscribed Lesion [NCIt concept]
Has associated anatomic sites
- Head and Neck [NCIt concept]
- Neck [NCIt concept]
- Thyroid Gland [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
disease_has_abnormal_cell
- Malignant Cell [NCIt concept]
- Malignant Cuboidal Mucous Cell [NCIt concept]
- Malignant Epithelial Cell [NCIt concept]
- Malignant Goblet-Like Mucous Cell [NCIt concept]
- Malignant Squamoid Cell [NCIt concept]
- Mucin-Producing Malignant Epithelial Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Epithelial Cell [NCIt concept]
disease_has_finding
- Carcinomatous Component Present [NCIt concept]
- Cystic Change [NCIt concept]
- Eosinophilic Infiltrate [NCIt concept]
- Epithelial Component Present [NCIt concept]
- Fibrotic Stroma Formation [NCIt concept]
- Lymphocytic Infiltrate [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
- Plasmacytic Infiltrate [NCIt concept]
disease_has_normal_cell_origin
- Epithelial Cell [NCIt concept]
disease_has_normal_tissue_origin
- Epithelial Tissue [NCIt concept]
- Thyroid Gland Epithelial Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Head and Neck [NCIt concept]
- Neck [NCIt concept]
- Thyroid Gland [NCIt concept]
disease_mapped_to_gene
- CRTC1/MAML2 Fusion Gene [NCIt concept]
disease_may_have_associated_disease
- Hashimoto Thyroiditis [NCIt concept]
disease_may_have_cytogenetic_abnormality
- t(11;19)(q21;p13) [NCIt concept]
disease_may_have_molecular_abnormality
- CRTC1-MAML2 Fusion Protein Expression [NCIt concept]

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