Selective Estrogen Receptor Modulator CC-8490

Preferred Label : Selective Estrogen Receptor Modulator CC-8490;

NCIt related terms : CC-8490;

NCIt definition : A benzopyran with potential antineoplastic activity. CC-8490 acts as a selective estrogen receptor modulator (SERM), inhibiting the proliferation of estrogen-sensitive breast cancer cells. This agent also inhibits growth and induces apoptosis of glioblastoma cells via a mechanism independent of estrogen receptor-related mechanisms. (NCI04);

Alternative definition : NCI-GLOSS: A substance that is being studied in the treatment of brain cancer. It belongs to the family of drugs called benzopyrans.;

Molecule name : CC-8490; SPC8490;

Codes from synonyms : CDR0000350227;

Details

Origin ID

C38711;

UMLS CUI

C1328106;

Currated CISMeF NLP mapping
- CC-8490 [MeSH concept]
- CC-8490 [MeSH Supplementary Concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- CC-8490 [MeSH concept]
- CC-8490 [MeSH Supplementary Concept]
concept_is_in_subset
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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