NCIt definition : A liposome-encapsulated formulation of the benzoquinazoline folate analog OSI-7904
with antineoplastic activity. As a thymidylate synthase inhibitor, OSI-7904 noncompetitively
binds to thymidylate synthase, resulting in inhibition of thymine nucleotide synthesis
and DNA replication. Liposome encapsulation improves the efficacy and increases the
half-life of OSI-7904. (NCI04);
Alternative definition : NCI-GLOSS: A substance that is being studied in the treatment of cancer. It belongs
to the family of drugs called thymidylate synthase inhibitors.;
UNII : ON177ZCE7M;
CAS number : 139987-54-5; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 139987-54-5
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