Ravuconazole - CISMeF

Preferred Label : Ravuconazole;

NCIt synonyms : p-(2-((alphaR,betaR)-2,4-Difluoro-beta-hydroxy-alpha-methyl-beta-(1H-1,2,4-triazol-1-ylmethyl)phenethyl)-4-thiazolyl)benzonitrile;

NCIt definition : A triazole with antifungal activity. Ravuconazole inhibits 14a demethylase, an enzyme involved in sterol synthesis, resulting in lysis of the fungal cell wall and fungal cell death. (NCI04);

Alternative definition : NCI-GLOSS: A substance that is being studied in the treatment of infections caused by fungi. It belongs to the family of drugs called antifungal agents.;

UNII : 95YH599JWV;

InChIKey : OPAHEYNNJWPQPX-RCDICMHDSA-N;

CAS number : 182760-06-1;

Molecule name : BMS-207147; ER-30346;

Chemical formula : C22H17F2N5OS;

Codes from synonyms : CDR0000340935;

Details

Origin ID

C38688;

UMLS CUI

C0535185;

Automatic exact mappings (from CISMeF team)
- ER 30346 [MeSH Supplementary Concept]
Currated CISMeF NLP mapping
- ravuconazole [MeSH concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- ravuconazole [MeSH concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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