NCIt definition : A humanized monoclonal immunoglobulin G1 antibody with potential antineoplastic activity.
Siplizumab binds to CD2, a specific receptor found in T cells and NK cells, thereby
triggering a host immune response that results in lysis of CD2 cells, selective suppression
of the immune system, and control of activated T cell growth.;
Alternative definition : NCI-GLOSS: A monoclonal antibody that is being studied in the treatment of certain
lymphoproliferative disorders and psoriasis.;
UNII : KUW1QG1ZM3;
CAS number : 288392-69-8;
Molecule name : MEDI-507;
Codes from synonyms : CDR0000367413; CDR0000367412;