" /> Amsilarotene - CISMeF





Preferred Label : Amsilarotene;

NCIt related terms : TAC-101;

NCIt definition : A retinobenzoic acid with potential antineoplastic activity. Amsilarotene inhibits retinoblastoma-gene product (RB) phosphorylation and increases the presence of 2 cyclin-dependent kinase (CDK) inhibitors, resulting in cell cycle arrest. This agent also causes a cytotoxic decline in cyclin A and thymidylate synthase expression.;

Alternative definition : NCI-GLOSS: A substance that is being studied in the treatment of cancer. It belongs to the families of drugs called synthetic retinoids and angiogenesis inhibitors.;

UNII : Q1418F39MH;

InChIKey : VVTNSTLJOVCBDL-UHFFFAOYSA-N;

CAS number : 125973-56-0;

Molecule name : TAC-101; TAC 101;

Chemical formula : C20H27NO3Si2;

Codes from synonyms : CDR0000367448;

Détails


Vous pouvez consulter :


Nous contacter.
29/07/2025


[Accueil] [Haut de page]

© CHU de Rouen. Toute utilisation partielle ou totale de ce document doit mentionner la source.