Colistin Sulfate

Preferred Label : Colistin Sulfate;

NCIt synonyms : Polymixin E Sulfate; N-(4-amino-1-(1-(4-amino-1-oxo-1-(3,12,23-tris(2-aminoethyl)- 20-(1-hydroxyethyl)-6,9-diisobutyl-2,5,8,11,14,19,22-heptaoxo- 1,4,7,10,13,18-hexaazacyclotricosan-15-ylamino)butan-2-ylamino)- 3-hydroxybutan-2-ylamino)-1-oxobutan-2-yl)-N,5-dimethylheptanamide;sulfuric acid;

NCIt definition : Cyclic polypeptide antibiotic from Bacillus colistinus. It is composed of Polymyxins E1 and E2 (or Colistins A, B, and C) which act as detergents on cell membranes. Colistin is less toxic than Polymyxin B, but otherwise similar; the methanesulfonate is used orally. (Medical Dictionary Online);

UNII : WP15DXU577;

CAS number : 1264-72-8;

Drug name : Coly-Mycin S;

Details

Origin ID

C386;

UMLS CUI

C0009317;

Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Antibiotic [UMLS semantic type]
Validated automatic mappings to NTBT
- Colistin [LOINC component]
- Colistin (substance) [SNOMED CT concept]
- colistin [MeSH Descriptor]
- colistin [MeSH concept]
- colistin [Substance BNPC]
- polymyxin e [SNOMED Notion]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
has_free_acid_or_base_form
- Colistin [NCIt concept]
is_component_of_chemotherapy_regimen
- Amphotericin B/Colistin Sulfate/Tobramycin [NCIt concept]
is_salt_form_of
- Colistin [NCIt concept]

Keyword's position in hierarchy(ies) :

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