Progonadoliberin-2

Preferred Label : Progonadoliberin-2;

NCIt synonyms : Gonadotrophin Releasing Hormone-2; Progonadoliberin 2; Progonadoliberin II; GNRH2;

NCIt definition : Progonadoliberin-2 (120 aa, 13 kDa) is encoded by the human GNRH2 gene. This protein is involved in the regulation of luteinizing hormone and follicle-stimulating hormone secretion.;

NCIt note : Progonadoliberin-2 is cleaved into 2 active peptides comprised of either amino acid residues 24-33, which is called gonadoliberin-2 (gonadoliberin II; gonadorelin; gonadotropin-releasing hormone II; GnRH-II; luliberin II; luteinizing hormone-releasing hormone II; LH-RH II), or residues 37-120, which is called GnRH-associated peptide 2 (GnRH-associated peptide II). (UniProt);

Details

Origin ID

C38494;

UMLS CUI

C1531431;

OMIM relation
- Gonadotropin-releasing hormone 2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Hormone [UMLS semantic type]
gene_encodes_gene_product
- GNRH2 Gene [NCIt concept]
- Peptide Hormone Gene [NCIt concept]
gene_product_expressed_in_tissue
- Hypothalamus [NCIt concept]
gene_product_plays_role_in_biological_process
- Intercellular Communication Process [NCIt concept]
- Protein Secretion [NCIt concept]
- Reproduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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