" /> 5-Hydroxypicolinaldehyde Thiosemicarbazone - CISMeF





Preferred Label : 5-Hydroxypicolinaldehyde Thiosemicarbazone;

NCIt synonyms : 5-HP; 5-Hydroxypicolinaldehyde Thiosemicarbazone;

NCIt related terms : 5-HYDROXYPYRIDINE-2-CARBOXALDEHYDE THIOSEMICARBAZONE;

NCIt definition : A thiosemicarbazone antimetabolite. A derivative of 5-hydroxypicolinaldehyde, 5-HP inhibits DNA polymerase, resulting in the inhibition of DNA replication and cell death. (NCI04);

NCIt note : Inhibits DNA synthesis by preventing incorporation of thymidine into DNA (chelates iron);

UNII : 7E4G242I83;

CAS number : 19494-89-4;

NSC code : 107392;

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12/12/2025


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