Pancreatic Intraductal Papillary-Mucinous Neoplasm

Preferred Label : Pancreatic Intraductal Papillary-Mucinous Neoplasm;

NCIt synonyms : Pancreatic IPMN; Pancreatic Intraductal Papillary-Mucinous Tumor;

CISMeF acronym : IPMN;

NCIt definition : A usually slow-growing epithelial neoplasm with ductal differentiation that arises from the exocrine pancreas and grows mostly within the pancreatic ducts. Grossly, it is characterized by the presence of intraductal masses. Morphologically, there is proliferation of mucin-producing cells within the pancreatic ducts, intraductal accumulation of mucin, and a papillary growth pattern. It may be associated with the presence of an invasive carcinoma. It usually occurs in older patients. Signs and symptoms include epigastric pain, weight loss, jaundice, chronic pancreatitis, and diabetes mellitus.;

Neoplastic status : Undetermined;

Détails

Origin ID

C38342;

UMLS CUI

C4511687;

Currated CISMeF NLP mapping
- Intraductal papillary mucinous carcinoma of pancreas [ORDO Disease]
- Intraductal papillary mucinous neoplasm of pancreas [ICD-11 More detail]
- Intraductal papillary mucinous neoplasm of pancreas (disorder) [SNOMED CT concept]
- intraductal papillary mucinous neoplasm [Radlex concept]
- pancreatic intraductal papillary-mucinous neoplasm [DO Concept]
DO Cross reference
- pancreatic intraductal papillary-mucinous neoplasm [DO Concept]
Disease excludes abnormal cell
- Neoplastic Smooth Muscle Cell [NCIt concept]
- Neoplastic Squamous Cell [NCIt concept]
Disease may have findings
- Abdominal Pain [NCIt concept]
- Cystic Change [NCIt concept]
- Diabetes Mellitus [NCIt concept]
- Jaundice [NCIt concept]
- Weight Loss [NCIt concept]
Has associated anatomic sites
- Digestive System [NCIt concept]
- Pancreas [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- Intraductal papillary mucinous neoplasm of pancreas (disorder) [SNOMED CT concept]
Validated automatic mappings to NTBT
- Pancreatic Intraductal Neoplasms [MeSH Descriptor]
concept_is_in_subset
- CTRP Disease Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- Cellosaurus Disease Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
disease_excludes_finding
- Mixed Neoplastic Glandular and Squamous Cell Population [NCIt concept]
- Tubular Pattern [NCIt concept]
disease_has_abnormal_cell
- Neoplastic Cell [NCIt concept]
- Neoplastic Epithelial Cell [NCIt concept]
- Neoplastic Glandular Cell [NCIt concept]
disease_has_finding
- Cystic Change [NCIt concept]
- Epithelial Component Present [NCIt concept]
- Intraductal Lesion [NCIt concept]
- Mucoid Stroma Formation [NCIt concept]
- Papillary Growth Pattern [NCIt concept]
disease_has_normal_cell_origin
- Epithelial Cell [NCIt concept]
disease_has_normal_tissue_origin
- Epithelial Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Exocrine Pancreas [NCIt concept]
disease_mapped_to_gene
- KRAS Gene [NCIt concept]
disease_may_have_associated_disease
- Diabetes Mellitus [NCIt concept]
- Pancreatitis [NCIt concept]
disease_may_have_cytogenetic_abnormality
- Loss of Chromosome 17p [NCIt concept]
- Loss of Chromosome 18q [NCIt concept]
- Loss of Chromosome 9p [NCIt concept]
disease_may_have_molecular_abnormality
- BRAF Gene Mutation [NCIt concept]
- KRAS Gene Mutation [NCIt concept]
- TP53 Gene Inactivation [NCIt concept]
pathogenesis_of_disease_involves_gene
- KRAS Gene [NCIt concept]
- KRAS wt Allele [NCIt concept]

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