" /> Buccal Route of Administration - CISMeF





Preferred Label : Buccal Route of Administration;

NCIt synonyms : BUCC; Buccal Route of Drug Administration;

NCIt related terms : Buccal use; Buccal;

NCIt definition : Administration of a substance through the mucosal membrane on the inside of the cheek or the back of the mouth. Buccal route bypasses first pass metabolism and avoids pre-systemic elimination in the gastrointestinal tract. The buccal environment is well supplied with both vascular and lymphatic drainage and is well suited for a retentive device. This is a feasible alternative for systemic delivery of orally inefficient drugs, such as peptide and protein drug molecules.;

Alternative definition : CDISC: Administration directed toward the cheek, generally from within the mouth. (FDA); EDQM-HC: Administration of a medicinal product to the buccal cavity (pouch located between the cheek and the gum) to obtain a systemic effect;

FDA table : Route of Administration (C-DRG-00301);

Codes from synonyms : 030; 20002500;

Details


Keyword's position in hierarchy(ies) : arborescence

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02/06/2024


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