NCIt synonyms : Ultrasmall Particulate Iron Oxide; USPIO;
NCIt definition : A synthetic ultrasmall superparamagnetic iron oxide composed of dextran-coated iron
oxide nanoparticles (also known as 'ultrasmall particulate iron oxides' or USPIO).
Ferumoxtran-10, which accumulates in non-cancerous lymphatic tissue, is used as a
molecular resonance imaging (MRI) contrast agent. (NCI04);
Alternative definition : NCI-GLOSS: A substance being studied as a way of improving magnetic resonance imaging
(MRI) in diagnosing cancer and finding lymph nodes to which cancer has spread. Ferumoxtran-10
is made of nanoparticles (ultrasmall pieces) of iron oxide coated with dextran (a
type of sugar). It is injected into the blood of the patient and the particles collect
in lymph nodes, liver, spleen, or brain tissue where they can be seen using MRI. Ferumoxtran-10
later breaks down and passes from the body in urine.;
Currated CISMeF NLP mapping