" /> Talampanel - CISMeF





Preferred Label : Talampanel;

NCIt synonyms : (R)-(-)-1-(4-Aminophenyl)-3-acetyl-4-methyl-7,8-methylenedioxy-3,4-dihydro-5H-2,3-benzodiazepine;

NCIt definition : A synthetic derivative of dioxolo-benzodiazepine with anti-seizure activity. Talampanel antagonizes the AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid) subtype of glutamate excitatory amino acid receptors and may inhibit the growth of gliomas by interfering with neurotransmitters involved in brain tumor growth. This agent may also protect against traumatic brain injury.;

Alternative definition : NCI-GLOSS: A substance that is being studied in the treatment of brain tumors and other brain disorders, such as epilepsy and Parkinson disease. It is a type of AMPA receptor antagonist.;

UNII : CVS43XG1L5;

InChIKey : JACAAXNEHGBPOQ-LLVKDONJSA-N;

CAS number : 161832-65-1; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 161832-65-1 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Molecule name : GYKI-53773; LY-300164;

Chemical formula : C19H19N3O3;

Codes from synonyms : CDR0000340938;

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12/05/2024


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