6-Aminonicotinamide

Preferred Label : 6-Aminonicotinamide;

NCIt synonyms : Aminonicotinamide; 6-AN; 6-Aminonicotinamide;

NCIt definition : A synthetic analogue and nicotinamide antagonist with cytotoxic properties, 6-Aminonicotinamide forms an abnormal NAD (ubiquitous metabolic pathway coenzyme) analog that inhibits NAD-dependent enzyme activity associated with ATP production. 6-Aminonicotinamide impairs cartilage formation, may have teratogenic effects, and enhances the effect of radiation and cisplatin treatment (formation of platinum-DNA complexes). (NCI04);

UNII : D6FNW67F2B;

CAS number : 329-89-5;

Molecule name : U-8774;

NSC code : 21206;

Details

Origin ID

C38127;

UMLS CUI

C0000610;

Automatic exact mappings (from CISMeF team)
- 4-O-carboxymethylascochlorin [MeSH Supplementary Concept]
- AS 6 [MeSH concept]
Currated CISMeF NLP mapping
- 6-Aminonicotinamide [MeSH Descriptor]
- 6-Aminonicotinamide [MeSH concept]
- 6-aminonicotinamide [Substance BNPC]
Semantic type(s)
- Pharmacologic Substance [UMLS semantic type]
- Vitamin [UMLS semantic type]
UMLS correspondences (same concept)
- 6-Aminonicotinamide [MeSH concept]
- 6-Aminonicotinamide [MeSH Descriptor]
- 6-aminonicotinamide [Substance BNPC]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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