Clotrimazole - CISMeF

Preferred Label : Clotrimazole;

NCIt synonyms : 1-[(2-Chlorophenyl)diphenylmethyl]-1H-imidazole; CLOT;

NCIt definition : A synthetic, imidazole derivate with broad-spectrum, antifungal activity. Clotrimazole inhibits biosynthesis of sterols, particularly ergosterol, an essential component of the fungal cell membrane, thereby damaging and affecting the permeability of the cell membrane. This results in leakage and loss of essential intracellular compounds, and eventually causes cell lysis.;

UNII : G07GZ97H65;

InChIKey : VNFPBHJOKIVQEB-UHFFFAOYSA-N;

CAS number : 23593-75-1;

Drug name : Mycelex; Lotrimin; Gyne-Lotrimin; Mycelex Troche;

Chemical formula : C22H17ClN2;

NSC code : 257473;

ChEBI ID : CHEBI:3764;

Codes from synonyms : 05194;

Details

Origin ID

C381;

UMLS CUI

C0009074;

Currated CISMeF NLP mapping
- Clotrimazole [ICD-11 Extension code]
- Clotrimazole [ICHI extension code]
- Clotrimazole [SMS substance]
- Clotrimazole [LOINC component]
- Clotrimazole (substance) [SNOMED CT concept]
- clotrimazole [International Nonproprietary Name]
- clotrimazole [Substance BNPC]
- clotrimazole [MeSH Descriptor]
- clotrimazole [MeSH concept]
- clotrimazole [SNOMED Notion]
False automatic mappings
- Blood clot (morphologic abnormality) [SNOMED CT concept]
- Clot [LOINC component]
- Clotted (qualifier value) [SNOMED CT concept]
- blood clot [UBERON concept]
- coagulation [GO term]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Clotrimazole [ICD-11 Extension code]
- Clotrimazole [LOINC component]
- Clotrimazole (substance) [SNOMED CT concept]
- Product containing clotrimazole (medicinal product) [SNOMED CT concept]
- clotrimazole [ATC Code]
- clotrimazole [ATC Code]
- clotrimazole [ATC Code]
- clotrimazole [Substance BNPC]
- clotrimazole [International Nonproprietary Name]
- clotrimazole [MeSH concept]
- clotrimazole [MeSH Descriptor]
- clotrimazole [SNOMED Notion]
Validated automatic mappings to BTNT
- clotrimazole [ATC Code]
- clotrimazole [ATC Code]
- clotrimazole [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
is_component_of_chemotherapy_regimen
- Bacitracin/Clotrimazole/Gentamicin [NCIt concept]

Keyword's position in hierarchy(ies) :

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