NCIt definition : Tissue structure disintegration and destruction due to action of endogenous or/and
exogenous lytic substances which include but not limited to naturally occurring or
laboratory designed proteolytic enzymes, glycosidases, detergents, pore-forming proteins,
immune complexes, etc. Tissue lysis plays role in pathogenesis of a number of conditions
e.g. protozoal infections, ischemic tissue injury, and autoimmune disorders. It is
also used as a basis for non-surgical treatment modality to remove or minimize presence
of abnormal tissue, e.g. adhesions.;